“Low T” or testosterone deficiency syndrome is a very popular topic these days, with men getting prescriptions for injections, gels, patches, and other T replacement options.

But is it safe? Are there side effects? What are the possible negatives to treatment of Low T? I cover what most medical professionals fail to tell you!

36 Comments
  1. Jim 6 years ago

    I understand what you are saying Will, however there aren’t really any appreciable side effects when managed by a competent physician (yes you allude to this in the video). My experience is that there aren’t masses of rogue docs prescribing testosterone inappropriately, rather it’s difficult to find a provider willing to prescribe, competent or otherwise.
    The most important take away from the video is to find a physician that understands corrective therapy. A fairly effective screening tool a patient can use to quickly determine a physician’s competency is to ask if they manage estradiol. If no, then they don’t know what whey are doing. If they do manage estrogen, it doesn’t necessarily mean they are competent, but will likely know more than a significant majority.

    • Author
      Will Brink 6 years ago

      Some good points Jim, but depends on what you’d consider “appreciable side effects” and the number of truly competent physicians in this area few and far between. The vast majority will simply diagnose low T, and prescribe T (and that’s if you can find one willing to do so at all as you point out) and that’s about it.
      Test for, much less manage E2, rare. Let men know their gonads will shrink, fertility shut down, HPTA shut down, etc, also rare in my experience, but slowly improving. Correct use of HCG both in timing and dose can maintain gonad function and fertility (if that’s important to the man), and good luck finding a doc who knows that and will prescribe for it, etc.
      Use of drugs such as Clomid and others to help maintain HPTA function, well, the above is tough enough and far outside the SOC for vast majority.
      Now, some men don’t care about the above, and that’s OK too, but they need to be made aware of it as a potential drawback, and most are not in my experience.

      • Lance 6 years ago

        The problem is much worse in Canada. Good luck finding a doctor that knows jack about T replacement and they will just supply the T and not check much else. Perhaps your next video should be on natural ways to increase T.

  2. Robert Buongiorno 6 years ago

    Dear Will,
    I’m a big fan of your web site and a former (satisfied) client of Monica Mollica. Regarding TRT, I’m 54 and this August I will have been on Androgel for a year. So far, happy with the results but recently I started talking to a local nutritionist who has recommended Pine Tree Pollen for TRT instead of prescription Androgel. Monica is of the opinion I should stay on Androgel but I was wondering if you had heard of Pine Tree Pollen and if it’s effective?
    Thank,
    Robert Buongiorno

    • Author
      Will Brink 6 years ago

      Any nutritionist who would recommend Pine Tree Pollen as TRT should have her license revoked. This is a license RD? No, Pine Tree Pollen will not replace legit T as prescribed by your doctor.
      I’d recommend finding a new nutritionist to work with.

      • Robert Buongiorno 6 years ago

        Will,
        Thanks so much for your reply. This is why I’m a fan!

  3. Fred 6 years ago

    Would appreciate more specific comments or possibly you could point to a book or article that discusses the potential negatives. Thank you.

  4. Jon DeVaul 6 years ago

    When I was on it, it was discovered that my red blood cell count rose. I was going to stay on it and just donate blood every 2-3 months, but we lost our health insurance, so I couldn’t afford it now anyhow.

    • Jim 6 years ago

      Polycythemia (increase in red blood cell volume) is the most appreciable side effect of testosterone supplementation. When red blood cell concentration is too high, blood viscosity can increase to the point where it can lead to obstructed blood vessels. The only way to deal with this is to lower your testosterone dose or give blood.
      In a decade of therapy, I have only had to donate blood 1 time and that was about 5 years ago…
      Actually there is one additional potential side effect that effects some men. Testosterone therapy can exacerbate or cause obstructive sleep apnea. It’s not a problem as long as treatment is also occurring with a CPAP.

  5. Christine Pincket 6 years ago

    Never did say what specifically are the side effects?!!!

    • Author
      Will Brink 6 years ago

      Yes, actually I did. I can’t cover them all (and most are rare) but did mention the most common, such as effects on fertility, testes shrink, etc.
      Point of the vid was to point out TRT is not as simply as giving out T gels and shot, and vast majority of docs don’t know that, as they don’t test for, much less control, E2, HPTA shut down, fertility issues, etc, which I mention in the vid. That’s the major point of the vid: TRT/HRT is (1) more complex than most people – including medical professionals who should know better – understand and (2) has some possible drawbacks people are often not made aware of.

  6. Mark 6 years ago

    In many cases, the proper dose, (intensity x duration x frequency), of exercise is the only prescription necessary to correct male hormonal balance, (I suppose creatine could be added to the equation), but for this be to be precise would require cooperation between a trainer and a doctor. Is there a facility where such work is being done?

    • Author
      Will Brink 6 years ago

      Not that I’m aware of no.

  7. Cal 6 years ago

    A good doc will monitor all kinds of things if you are put on TRT (regular blood tests). A good doc will go through a whole list of issues that you should be concerned with (Will mentioned some). If you think the patches and gels that are advertized on TV will increase your T levels you’re mistaken. Getting the T shots or pellets is NOT the same as taking steriods. So if you think you’re going to pack on extra muscles as a result of the TRT you won’t. How do I know this? I’m on TRT.

    • Author
      Will Brink 6 years ago

      Cal, one should indeed notice an improvement in body comp (less BF and more LBM) when on TRT and studies find most do. It’s not going to the to the level of those taking high doses of AAS for obvious reasons, but one benefit of TRT is improvements in body comp when going from a state of low T to high normal T withing physiological range.

      • Cal 6 years ago

        Yes I have seen some change in body composition. I’ve never really had a lot of excess weight, so the changes haven’t been huge. Will, your information is the best. Please keep feeding us good information.

  8. Jeff Johnson 6 years ago

    Off Topic Question: Why don’t you see movie stars having hair replacement(hair implants) ?

    • Author
      Will Brink 6 years ago

      You do. Lots have and it’s easy to spot.

  9. Tony 6 years ago

    What about these naural boosters that are not a “T-shot”. (I take TBoost?) pills that are extracts and fruits etc. would they still have same side effects?

    • Author
      Will Brink 6 years ago

      They will not and are generally a waste of $$$. I have a lengthy article here covering “T Booster” supplements you can read, as well as other articles vids on Testosterone (benefits, TRT, etc)

      • Tony 6 years ago

        Funny thing is ……….. (I thought it was kind of a scam?) I am 41, and since I began taking it – I too am leaner, feel stronger, Can workout more (less pain after). I am very impressed (And I take one pill a day not the recommended 2). So yeah – I am happy it is “psuedo-natural” vs. The Shots / Gels.

        • Author
          Will Brink 6 years ago

          If you feel it’s helping, it’s your $$$, but only regular blood work will tell you if it’s actually doing anything to your T levels, and it’s no replacement for medical TRT.
          Good luck

          • Kyle Davis 3 years ago

            The problem is many of the T boosters might help to a certain degree but in the long run the body starts to produce less and less T on its own and the body then is forced to become dependent on HRT as a permanent therapy. This happened in my case. I used over the counter boosters in my early 40’s on the recommendation of my trainer and my T levels fell to the 50’s as a result and I am on HRT now. I go to a Dr. that specializes in HRT and has a background in the area. He does not follow the typical protocol most general practitioners do that have little knowledge in this area. he uses a compound instead of the typical treatments and I am confident that in the long run the therapy will not only be the most beneficial but correct way to manage my condition. The videos are great resources Will thanks for taking the time to help educate peole about this subject!!

  10. joseph iacobellis 6 years ago

    what’s HCG?

    • Author
      Will Brink 6 years ago

      human chorionic gonadotropin.

  11. David Andrews 6 years ago

    Hi Will, informative as usual (and I like your articles at Life Extension and Life Enhancement). When you debunked the HCG-enhancers (previous video), you didn’t mention HGH enhancers. Are any of them useful, or are there reasons to avoid increasing your HGH? There is product called “Serovital” that has gotten some good press, but…

    • Author
      Will Brink 6 years ago

      I cover HGH boosters in my Body Building Revealed Program and The Sports Supplement Bible, either which would save you years of wasted time and $$ on supplements.
      BBR also includes nutrition and training and other tools and will pay for itself 10X over.
      I may do a vid on HGH boosters, which has no relation to HCG, so no reason to be included in this particular vid. 🙂

  12. Doug 6 years ago

    Will, you mention HCG as an alternative to keep the testes producing T. Do you know anything about DAA and whether it is actually useful? I’m 55 and I gave it a try. Didn’t have blood tests done before and after, but while I was using it I had more strength in my workouts, stopped falling asleep after dinner and seemed to have more stamina in the bedroom. Just curious about whether this could be a placebo effect, or the real thing.

    • Author
      Will Brink 6 years ago

      See my comments above on “T Booster” supplements. DAA has some interesting effects, but lacks useful data and no OTC “Booster” I’m aware of is legit replacement for TRT.
      Get blood work done. See my articles here on blood work called: “It’s In Your Blood”

  13. George Voirol 6 years ago

    Please, when you have a video about an important topic, include a written version, like before the videos became popular. Reading an article is quicker for me, and time is a factor when learning about your information posts. Thank you very much.
    George M. Voirol

    • Author
      Will Brink 6 years ago

      I will not be able to write a full article with the vids as that would totally negate the reason I do the vids: they allow me to get information out rapidly and timely, where as articles can take hours to days or longer.
      The vast majority of people respond better to visual and audio than they do to text, especially in the electronic age.

  14. Kent Ingram 6 years ago

    This has been a big concern of mine, especially at this age. I agree that an initial diagnosis should be made, first, and then go on from there. I guess I’d just like some of this middle-age-thing to be more pleasant and have a shot at looking better, physically, than I do, now. But, the cosmetic appearance at my age is less important than my overall health. Thanks, Will, for your reasoned approach. I’ll be calling the doc, soon.

    • Robert Buongiorno 6 years ago

      I’m 54 and on prescription TRT that was agreed to between my doctor & nutritionist. Low T is not something you should experiment with, go see your doctor, get a blood test and fully understand the risks as they apply to your particular situation. Contrary to what you may read at the supplement stores, you cannot boost T with anything over the counter. You’ll waste a lot of money chasing after the end of the rainbow!

  15. Bob Kent 6 years ago

    I have been on TRT for many years now. I was diagnosed with Follicular lymphoma 3 years ago.. It was level 4. I received the “CHOP” Treatment. I feel if it wasn’t for the TRT I would have not had the strength to continue working out and striving to overcome the cancer. I DID LOSE SOME POUNDS, BUT LUCKILY IT WAS ALL FAT. The TRT kept my lean muscle intact through the entire treatment. Now 3 years later I am in remission and still working out feeling great.

    • Author
      Will Brink 6 years ago

      Sounds like you have made excellent rebound to good health Bob and the TRT has assisted with that. Good deal. 🙂

  16. ARTURO 6 years ago

    UP’S ! I’M IN MY 40’S.

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