Below is a side bar from a lengthy article I recently wrote on the latest studies covering the many potential benefits of creatine. This short side bar covers the possible contraindications of creatine

Are there any contraindications Of Creatine Monohydrate?

Hundreds of studies to date have shown that creatine monohydrate is an amazingly non-toxic and safe supplement with numerous benefits. Further studies directly examining possible side effects, both prospective and long-term retrospective (up to five years), have failed to find any serious side effects of creatine supplementation (65-69) on various markers studied, such as renal function, hepatic function, and others. So are there contraindications of creatine monohydrate?

Although creatine monohydrate is clearly safe for healthy people with a very low side-effects profile using up to 10 grams per day, are there specific groups who should not use it?

Again, the data suggest very few actual contraindications. The only people who should avoid creatine supplements are those with a history of renal disease and/or those taking nephrotoxic (poisonous to the kidneys) medications. There’s been a handful of case reports that show very high doses of creatine (and the reports were not always clear as to what form of creatine was used) were associated with kidney dysfunction.(70) Typical for such a simple case report, it’s unclear what other medications were involved or pre-existing medical condition existed.

However tenuous the connection between high-dose creatine monohydrate and pre-existing kidney dysfunction, it’s prudent to advise people with a history of renal disease and/or those taking nephrotoxic medications to avoid creatine supplementation until more data exists examining that connection. As creatine monohydrate supplementation may cause a transient increase in creatinine levels in some individuals, it may act as a false indicator of renal dysfunction.

Full Article HERE

9 Comments
  1. Joe 5 years ago

    I have read that it is a good idea to cycle off creatine periodically For the last few years I have been supplementing with creatine about ten months per year when I am generally heavy lifting and do not supplement with it in the summer when I am doing more cardio, still lifting but generally not as heavy nor quite as often, Do you think that makes sense I have had some liver red flags before I started creatine, but that problem seems to have abated since improving my diet

    • Author
      Will Brink 5 years ago

      I cover cycling in my vid series on creatine which answers the most common Qs on creatine. You can find them by looking in the “Topics” section at the top of the page. There’s no reason to cycle creatine and no harm done if you wish to.

  2. Wes Turner 5 years ago

    Will
    How does insulin spiking affect creatine and how out body processes creatine?

  3. Suresh Shukla 5 years ago

    Hi Will,
    While there are said to be no major side effects of creatine, I have come across many people – personally as well as on internet – who say that it leads to a rapid Hair loss. Does this assumption hold water?
    Thanks

    • Author
      Will Brink 5 years ago

      Nope. There was a single poorly conducted study done in rugby players that showed an increase in DHT, not seen in any studies before or after, and from that, bro science types will not let go of the mythology that creatine = hair loss. It’s complete nonsense.

      • sean 5 years ago

        Will, I noticed LEF isn’t offering the Creatine Monohydrate in powder form, just capsules.
        Do you know of another good source?

        • Author
          Will Brink 5 years ago

          Any company that uses CreaPure as it’s source is fine. A Google search will turn u
          various choices. I’d also let the LEF know you wanted to buy it from them,
          but want powder vs caps. They tend to be a very response company that way,
          and enough people tell them and they will bring back the powder I bet.

          • sean 5 years ago

            Thanks

  4. wes turner 5 years ago

    Can one get more out of creatine by timing it with an insulin spike? Is the data on this subject inconclusive at this time?
    thanks
    wes

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