Clinical practice guidelines rely heavily on results from randomized controlled trials (RCTs), which is the gold standard for medical...
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Long-term testosterone treatment with different testosterone preparations – provocative results on diagnosis and adherence

Due to lack of consistent clear-cut guidelines for diagnosis and treatment of testosterone deficiency, there is a lot of...
It is well documented that obesity may cause hypogonadism, and that hypogonadism may cause obesity This has generated...
What are Bioidentical Hormones? Don't get fooled by marketing claims!

The term bioidentical hormone does not have a standardized definition and thus often confuses patients and practitioners. The Endocrine...
Estrogen Elevations in Response to Testosterone Therapy – to treat or not?

During testosterone therapy, total and free estradiol (the main form of estrogen) levels increase dose-dependently in both young (aged...
Multiple beneficial effects of testosterone replacement therapy (TRT) in men with testosterone deficiency

Alleged concerns regarding risk of cardiovascular disease with testosterone replacement therapy (TRT) have been promulgated recently. However, a large...
Adverse health effects of testosterone deficiency, aka hypogonadism, in men

Testosterone deficiency, also known as hypogonadism, is a state with sub-optimal circulating levels of testosterone concomitant with clinical signs...
Testosterone Treatment and Heart Attack Risk – New study shows testosterone treatment can actually be beneficial

Testosterone therapy has been in use for more than 70 years for the treatment of hypogonadism, also called testosterone...
Association of IGF-1 with Mortality, Cardiovascular Disease, and Cancer

IGF-1 (insulin-like growth factor-1) is a peptide hormone, produced predominantly by the liver in response to pituitary GH (growth...
Effects of 6-year Long-Term Testosterone Replacement Therapy (TRT) in Patients with ‘‘Diabesity’’

March 6th 2014 FDA approved Aveed for treatment of male hypogonadism, aka testosterone deficiency.1 Aveed is a long-acting form of...


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